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RT-PCR and western blotting Evaluation had been carried out to analyze the underlined molecular system that Lycorine exerted on EGFR alone and EGFR signaling pathway. 3 unique xenograft styles (an U251-luc intracranially orthotopic transplantation design, an EGFR stably knockdown U251 subcutaneous xenograft design and a affected person-derived xeno